While the dilemma of defining what constitutes true knowledge will be endlessly debated, I would like to present a simple thought on the acquisition of such knowledge.
Acquiring knowledge is the conversion of empirical information into a perfect a priori form.
By perfect a priori form I intend to say that it can be re-formulated, and arrived to, without relying on any empirical information. In this scenario we can explain any part of reality by relying on concepts describing the building blocks of reality, and considering the logical (unambiguous) consequences of these concepts at the scale of inquiry (i.e. hierarchical position of subject).